Sep 19, 2019 · Preferred dose for dexamethasone is 2 mg every 6 h or 4 mg every 12 h
Currently in USSOCOM operations, there is an option
There was no evidence of adrenal cortical suppression after treatment with dexamethasone or placebo 48 h after discontinuing altitude exposure and drug treatment
In high altitudes, usually accepted as above 2500 m, travelers are faced with decreased partial pressure of oxygen along with decreased barometric pressure
Applies to the following strengths: 0
5 mg/5 mL; 4 mg/mL; 8 mg/mL; 24 mg/mL; 10 mg/mL; 1 mg/mL; 1 mg; 2 mg; 16
Abstract Background AMS is a disease that occurs when accessing high altitude (HA) or upon exposure to a higher altitude after acclimatising over 3000 m
Acute mountain sickness (AMS) is a syndrome induced by hypobaric hypoxia in individuals who ascend rapidly to altitudes above 2500
At over 3,000 metres (10,000 feet) 75% of people will have mild symptoms
A meta-analysis reveals that oral dexamethasone (8, 12, and 16 mg/day) could effectively prevent AMS
Treatment with high-dose dexamethasone is not recommended beyond 2 to 3 days
For example, you may get a headache when This paper aims to provide a comprehensive review of high-altitude sickness, including its epidemiology, pathophysiology, and treatments
In severe cases, the abrupt change in altitude can lead to cerebral or pulmonary edema
It is taken orally in a dose of 125 mg twice a day
Dexamethasone (DEX) can be taken prophylactically to prevent HA disease, but the mechanism by which it acts in this setting is Abbreviations: AMS, acute mountain sickness; HACE, high-altitude cerebral edema; HAPE, high-altitude pulmonary edema; IM, intramuscular; IV, intravenous; PO, by mouth; SR, sustained release
High altitude
2 mg PO q6hr or 4 mg PO q12hr beginning on day of ascent; may be discontinued after 2- to 3-day stay at same elevation or initiation of Johnson et al
23–21
Other forms of high-altitude illness are discussed separately
Prophylactic low-dose acetazolamide reduces the incidence and severity of acute