Last updated on Dec 11, 2023
Dosage Considerations – Should be Given as Follows: Primary Hyperaldosteronism As a
3 DOSAGE FORMS AND
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Treatment should be initiated with spironolactone 25 mg once daily if the patient’s serum potassium is ≤5
It is unknown to what extent, if any
Spironolactone is used to help manage refractory edema or fluid retention due to congestive heart failure, cirrhosis of the liver, ascites, hypertension, feline primary hyperaldosteronism, and nephrotic syndrome
Also find the prescribing information, announcements, resources, and channels to connect with Pfizer Medical Information 3 DOSAGE FORMS AND STRENGTHS
For oral dosage form (tablets): Adults—At first, 100 milligrams (mg) per day, taken in either single or divided doses
Once acne is reduced, the recommended maintenance dosage ranges usually from 25 – 50mg per day
Dosage forms for topical spironolactone use include gels of 1% and solutions of 5% twice daily
Standard Dosage: Heart failure: 25 to 50 mg once daily: Hypertension: Total daily doses of 25 to 100 mg given in a single dose or divided doses: with food substantially increases the body’s absorption of spironolactone and the plasma concentration of its active form
Tablets: 25 mg, 50 mg, and 100 mg
When given as the sole agent for diuresis, administer for at least five days before increasing dose to obtain
Your dose may need to be changed a few times before you find the dose that's right for you
Spironolactone is available in tablet and liquid forms in the following strengths:⁵
Spironolactone is contraindicated in the patients with: Hyperkalemia - Addison’s disease DOSAGE FORMS AND STRENGTHS
Film-coated tablet