This combination product contains two ingredients: naproxen and sumatriptan
When the starting headache intensity was mild, 5 in 10 (50%) of people treated with the combination were pain-free at two hours compared with about 2
Gastrointestinal bleeding, ulceration, and perforation: NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including
Sumatriptan and naproxen sodium is contraindicated in the setting of coronary artery bypass graft (CABG) surgery ( 4, 5
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An aura is a strange feeling or visual disturbance that warns you of an attack
Last updated on May 11, 2022
stomach discomfort, upset, or pain
Two different triptans in the same day
Sumatriptan is in a class of medications called selective serotonin receptor agonists
Note: The safety of treating an average of >5 migraine headaches in a 30-day period has not been established
Other side effects not listed may also occur in some patients
Risk cannot be ruled out
an allergy to sumatriptan or any of the ingredients in sumatriptan tablets
One study that evaluated the naproxen and sumatriptan combo concluded the following: Sumatriptan, 85 mg, plus naproxen sodium, 500 mg, as a single tablet for acute treatment of migraine resulted in more favorable clinical benefits compared with either monotherapy, with an acceptable and well-tolerated adverse effect profile
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Each TREXIMET Tablet for oral administration contains 119 mg of sumatriptan succinate equivalent to 85 mg of sumatriptan and 500 mg of naproxen
Recuerde, mantenga ésta y todas las otras medicinas fuera del alcance de los niños, no comparta nunca sus medicinas con otros, y use este medicamento solo para la condición por la que fue recetada
An aura is a strange feeling or visual disturbance that warns you of an attack
More subjects using sumatriptan/naproxen achieved sustained pain freedom (than 2-hour pain freedom), due to 6 time points when the subject was sleeping/napping 2-hours post dose (5 sumatriptan/naproxen, 1 placebo), yet attested to no discomfort between 2 and 24 hours post dose
Objectives: To determine the efficacy and tolerability of sumatriptan plus naproxen, administered together as separate tablets or taken as a fixed-dose combination tablet, compared with placebo and other active interventions in the
This information does not contain all possible interactions or adverse effects