It is important to remember that QT prolongation can result from multiple factors, either multiple drugs or a combination of drugs and non-drug factors 5
With regards to drugs, the risk of QT prolongation and TdP varies markedly across the list but tends to
The QTc is considered prolonged if the values are greater than 450 milliseconds in males and greater than 470 milliseconds in females
Rohit Mohindra Sophie Gosselin Alexandre
We thank Ray and Skellett for highlighting the need for cardiac monitoring
Long QT syndrome is a disorder of myocardial repolarization that
The aim of the present study was to elucidate the relationship between serum lithium concentration and QT interval in patients Introduction
QT (QTc) Prolongation is associated with many psychotropic medications (especially antipsychotics) and some are linked to serious ventricular arrhythmias (e
• QT prolongation – Caution is advised in patients with risk factors for QT prolongation
58 However, remaining within the recommended dose and exercising additional caution is required in the older patient who may be at increased risk of adverse events compared
This increase in Drug-induced QT-Prolongation and Torsades
QT prolongation, due to lengthening of the action potential duration in the ventricles, is a major risk factor of lethal ventricular arrhythmias
2016 Jun;2(3):277-278
This was a single-center, prospective cohort analysis of ICU patients who received quetiapine between October 2015 and February 2016
An interaction between two medications does not always mean that you must stop taking one of the medications;
Stopping a seizure medicine suddenly can cause seizures that will not stop (status epilepticus)
*This list is not comprehensivebut is meant to be a practical list for those clinicians managing patients with LQTS in Canada
Alti-Valproic
Data sources: Primary literature and case reports were identified through a systematic search
If this occurs, i
Over the past year, three articles have appeared in the New England Journal of Medicine describing conflicting findings about azithromycin and cardiac safety, particular azithromycin-induced QTc interval prolongation and torsade de pointes
The new information does not change any of the recommended oral dosing regimens for Moxifloxacin