It is used to treat Paget’s disease
Oral
Drug class: Bisphosphonates
Proveedores de
Recommendations for Calcium and Vitamin D Dosis
The risk may be higher with longer use, cancer, dental problems, ill-fitting dentures, anemia, blood clotting problems, or infection
constipation
If these effects are mild Hypertension (high blood pressure)—Use with caution
Osteoporosis causes bones to become thinner and break more easily
As in Alendronate sodium tablets, USP for oral administration contain 13
Most alendronate (Fosamax) side effects are mild, such as heartburn, headaches, and constipation or diarrhea
Bisphosphonates are synthetic analogs of pyrophosphate that bind to the hydroxyapatite found in bone
It helps prevent fractures effectively by inhibiting the activity of bone cell and increasing bone density, which can be explained by retarding the formation of hydroxyapatite crystals for its combination
Kondisi: Osteoporosis yang disebabkan oleh efek samping
It works by slowing the breakdown of bones so that the body has a chance to build up more bone; this strengthens bones and lowers the risk of fractures
3) Treatment of glucocorticoid-induced osteoporosis ( 1
2) Treatment to increase bone mass in men with osteoporosis Treatment of glucocorticoid-induced osteoporosis Treatment of Paget's disease of bone Important limitations of use: The
Following a single IV dose of [14 C]alendronate, approximately 50% of the radioactivity was excreted in the urine within 72 hours and little or no radioactivity was recovered in the feces
The empirical formula of alendronate sodium is C 4 H 12 NNaO 7 P 2 •3H 2 O and its formula weight is 325
Take alendronate sodium tablets while you are sitting or standing
1 Mechanism of Action - Alendronate Sodium - Animal studies have indicated the following mode of action
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